Reference Standards
Material, sufficiently homogeneous and stable with respect to one or more specified properties, and the uses include the calibration of a measurement system, assessment of a measurement procedure, assigning values to other materials, and quality control and so on.
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Reference Standards Related Products (11493)
Related Products (11493)
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Alisertib (Standard)
0 ImagesCat. No.: HY-10971RCAS No.: 1028486-01-2Synonyms: MLN 8237 (Standard)Alisertib (Standard) is the analytical standard of Alisertib. This product is intended for research and analytical applications. Alisertib (MLN 8237) is an orally active and selective Aurora A kinase inhibitor (IC50=1.2 nM), which binds to Aurora A kinase resulting in mitotic spindle abnormalities, mitotic accumulation. Alisertib (MLN 8237) induces apoptosis and autophagy through targeting the AKT/mTOR/AMPK/p38 pathway in leukemic cells. Antitumor activity.
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SB-328437 (Standard)
0 ImagesCat. No.: HY-103363RCAS No.: 247580-43-4SB-328437 (Standard) is the analytical standard of SB-328437 (HY-103363). This product is intended for research and analytical applications. SB-328437 is a potent, selective non-peptide CCR3 antagonist with an IC50 of 4.5 nM. SB-328437 can inhibit eosinophil migration induced by eotaxin, eotaxin-2, and monocyte chemotactic protein-4. In addition, SB-328437 can sensitize 5-FU (HY-90006)-resistant gastric cancer cells. SB-328437 can also reduce the recruitment of neutrophils to the lungs and pulmonary inflammation during acute inflammation. SB-328437 can be used in the research of inflammation-related diseases.
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Clindamycin (Standard)
0 ImagesClindamycin (Standard) is the analytical standard of Clindamycin. This product is intended for research and analytical applications. Clindamycin is an orally active and broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin can inhibit bacterial protein synthesis, possessing the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla). Clindamycin also can be used for researching malaria.
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Tacrine (Standard)
0 ImagesTacrine (Standard) is the analytical standard of Tacrine. This product is intended for research and analytical applications. Tacrine is an effective oral acetylcholine (AChE) inhibitor (IC50 = 109 nM) and also acts as an active substrate for CYP1A2. Tacrine can restore cognitive dysfunction in elderly rats. Tacrine can cause liver toxicity and is used in research related to Alzheimer's disease.
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Sauchinone (Standard)
0 ImagesCat. No.: HY-N0613RCAS No.: 177931-17-8Sauchinone (Standard) is the analytical standard of Sauchinone. This product is intended for research and analytical applications. Sauchinone is a diastereomeric lignan isolated from Saururus chinensis (Saururaceae). Sauchinone inhibits LPS-inducible iNOS, TNF-α and COX-2 expression through suppression of I-κBα phosphorylation and p65 nuclear translocation. Sauchinone has anti-inflammatory and antioxidant activity.
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(±)-Alliin (Standard)
0 ImagesCat. No.: HY-126085RCAS No.: 17795-26-5Synonyms: (±)-L-Alliin (Standard)(±)-Alliin (Standard) is the analytical standard of (±)-Alliin. This product is intended for research and analytical applications. (±)-Alliin is the main active component of garlic. (±)-Alliin is a putative inhibitor of the main protease of SARS-CoV-2 (Mpro).
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Carboxyamidotriazole (Standard)
0 ImagesSynonyms: L-651582 (Standard); CAI (Standard)Carboxyamidotriazole (Standard) is the analytical standard of Carboxyamidotriazole. This product is intended for research and analytical applications. Carboxyamidotriazole (L-651582) is a cytostatic inhibitor of nonvoltage-operated calcium channels and calcium channel-mediated signaling pathways. Carboxyamidotriazole shows anti-tumor, anti-inflammatory and antiangiogenic effects.
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Pralidoxime chloride (Standard)
0 ImagesPralidoxime (chloride) (Standard) is the analytical standard of Pralidoxime (chloride). This product is intended for research and analytical applications. Pralidoxime chloride is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime chloride reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime chloride is an antidote for organophosphate poisoning.
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Benzcyclane (Standard)
0 ImagesCat. No.: HY-U00134RCAS No.: 2179-37-5Synonyms: Bencyclane (Standard); Benzcyclan (Standard)Benzcyclane (Standard) is the analytical standard of Benzcyclane (HY-U00134). This product is intended for research and analytical applications. Benzcyclane (Bencyclane; Benzcyclan) is a vasodilator with serotonin receptor antagonism. Benzcyclane exerts atypical serotonin antagonistic effects in rabbit superior mesenteric arteries. Benzcyclane relaxes high K+-induced contractions in rabbit basilar arteries and superior mesenteric arteries, and selectively inhibits sympathetic nerve stimulation-induced contractions in rabbit pulmonary arteries. Benzcyclane exerts non-competitive norepinephrine antagonistic effects in rabbit superior mesenteric arteries, and slightly reduces the maximum contractile response induced by histamine. Benzcyclane relaxes smooth muscles, induces transient hypotension, inhibits thrombosis, and accelerates blood fibrinolytic activity. Benzcyclane increases cerebral glucose content/uptake, enhances hypoxia tolerance in mice, and increases cerebral blood supply in dogs. Benzcyclane is applicable to studies related to cerebral vascular circulation.
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Lucerastat (Standard)
0 ImagesSynonyms: NB-DGJ (Standard); N-(n-Butyl)deoxygalactonojirimycin (Standard)Lucerastat (Standard) is the analytical standard of Lucerastat. This product is intended for research and analytical applications. Lucerastat, the galactose form of Miglustat, is an orally-available inhibitor of glucosylceramide synthase (GCS). Lucerastat has the potential for Fabry disease study.
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Murrayafoline A (Standard)
0 ImagesCat. No.: HY-W100287RCAS No.: 4532-33-6Murrayafoline A (Standard) is the analytical standard of Murrayafoline A (HY-W100287). This product is intended for research and analytical applications. Murrayafoline A is a carbazole alkaloid that can be extracted from Murraya tetramera. Murrayafoline A directly targets Specificity protein 1 (Sp1), thereby inhibiting NF-κB and MAPK signaling pathways. Murrayafoline a induces a G0/G1-phase arrest in platelet-derived growth factor (PDGF)-stimulated vascular smooth muscle cells. Murrayafoline A attenuates the Wnt/β-catenin pathway by promoting the degradation of intracellular β-catenin proteins. Murrayafoline A enhances the contraction of rat ventricular myocytes and L-type calcium current by activating protein kinase C. Murrayafoline A inhibits LPS (HY-D1056)-induced neuroinflammation in vivo. Murrayafoline A can be used for the study of inflammation, vascular complications and colon cancer.
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GSK1059865 (Standard)
0 ImagesCat. No.: HY-101534RCAS No.: 1191044-58-2GSK1059865 (Standard) is the analytical standard of GSK1059865 (HY-101534). This product is intended for research and analytical applications. GSK1059865 is a potent orexin 1 receptor antagonist.
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Idazoxan hydrochloride (Standard)
0 ImagesCat. No.: HY-14561ARCAS No.: 79944-56-2Synonyms: RX 781094 hydrochloride (Standard)Idazoxan (hydrochloride) (Standard) is the analytical standard of Idazoxan (hydrochloride). This product is intended for research and analytical applications. Idazoxan hydrochloride (RX 781094 hydrochloride) is an α2-adrenoceptor antagonist and is also a imidazoline receptors (IRs) antagonist competitively antagonized the centrally induced hypotensive effect of imidazoline-like agents (IMs). Idazoxan hydrochloride also improves motor symptoms in Parkinson’s disease, L-DOPA-induced dyskinesias, and experimental Parkinsonism.
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SDZ-MKS 492 (Standard)
0 ImagesCat. No.: HY-100164RCAS No.: 114606-56-3Synonyms: MKS 492 (Standard)SDZ-MKS 492 (Standard) is the analytical standard of SDZ-MKS 492 (HY-100164). This product is intended for research and analytical applications. SDZ-MKS 492 (MKS 492) is a selective inhibitor of cyclic GMP-inhibited phosphodiesterase (type III PDE). SDZ-MKS 492 inhibits antigen- or platelet activating factor (PAF)-induced bronchoconstriction and allergic reactions in guinea pigs and rats.
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3-Methylsalicylic acid (Standard)
0 ImagesSynonyms: o-Cresotic acid (Standard); Hydroxytoluic acid (Standard)3-Methylsalicylic acid (Standard) is the analytical standard of 3-Methylsalicylic acid. This product is intended for research and analytical applications. 3-Methylsalicylic acid (o-Cresotic acid) is a derivative of salicylic acid. 3-Methylsalicylic acid exhibits significant fibrinolytic activity in human plasma by activating the fibrinolytic system. 3-Methylsalicylic acid can be used as an intermediate for the synthesis of other compounds. 3-Methylsalicylic acid inhibits the feeding of midges.
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Ticagrelor impurity 12 (Standard)
0 ImagesCat. No.: HY-78540RCAS No.: 220241-61-2Ticagrelor impurity 12 (Standard) is the analytical standard of Ticagrelor impurity 12 (HY-78540). This product is intended for research and analytical applications.
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Phthaloylamlodipine (Standard)
0 ImagesCat. No.: HY-137163RCAS No.: 88150-62-3Synonyms: Phthaloyl Amlodipine (Standard)Phthaloylamlodipine (Standard) is the analytical standard of Phthaloylamlodipine. This product is intended for research and analytical applications.
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YM-58790 (Standard)
0 ImagesCat. No.: HY-101679RCAS No.: 214558-72-2YM-58790 (Standard) is the analytical standard of YM-58790 (HY-101679). This product is intended for research and analytical applications. YM-58790 is a potent antagonist of mAChR. YM-58790 binds M1, M2, M3 with Ki values of 28 nM, 260 nM, and 15 nM. YM-58790 exhibits potent inhibitory activity on bladder pressuer in reflexly-evoked rhythmic contraction in rats.
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Itacnosertib hydrochloride (Standard)
0 ImagesCat. No.: HY-109179ARCAS No.: 2409543-84-4Synonyms: TP-0184 hydrochloride (Standard)Itacnosertib hydrochloride (Standard) is the analytical standard of Itacnosertib (hydrochloride) (HY-109179A). This product is intended for research and analytical applications. Itacnosertib hydrochloride (TP-0184 hydrochloride) is the inhibitor for FLT3, ACVR1 (ALK2, IC50=8 nM) and JAK2 (IC50=8540 nM). Itacnosertib hydrochloride exhibits anti-leukemic activity.
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Cinaciguat (Standard)
0 ImagesCat. No.: HY-14181RCAS No.: 329773-35-5Synonyms: BAY 58-2667 (Standard)Cinaciguat (Standard) is the analytical standard of Cinaciguat. This product is intended for research and analytical applications. Cinaciguat is an activator of guanylate cyclase (sGC), and used for acute decompensated heart failure.
